Top Definition
(Sha-miss-coe) A SON OF A BITCH. Bastard, Asshole, Shithead, and Fucking Backstabber.
Man 1: " Dave! You slept with my women."
Man 2: "Damn right!..and it was GREEEAAT!
Man 1: "Dave your a shamisco."
Man 2: "!"
Man 1: It's alright I'll just slip some razer blades into your mashed potatoes."
by Blevint December 15, 2008
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