Top Definition
Named after the Ex-Philadelphia Inquirer photojournalist/Volunteer Fireman/Businessman. Has met several famous people during his tenure as a photojournalist such as Chevy Chase, President George H. Bush, and several other important figures in the 90's. To be Sean P. Duffy, you have to be a complete boss in any situation your in while being quick-witted and intelligent, making the opposing person of said conversation feel dumb or blessed to be in the presence of such a legend.
Andrew: Hey Sam why is Matt talking so much crap behind my back?
Sam: Idk man, all I know is that you better go Sean P. Duffy on him and show him the business.
by Steven Buhrts-Hansen February 23, 2011

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