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1.
a derogatory term referring to the religious cult of Scientology.
Did u know Sci Scis gather annually to an island and eat fecal matter for 3days straight?
by jewslammer February 07, 2009
 
2.
A close indian friend who's slightly strange.

A friend who's a scisci is a scisci for life!
Sci sci! Afnan! How've you been?
by sciscino.1 June 10, 2013