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Derived from from the 'Saw' films, this term describes when something so shockingly unpredictable happens that it makes you unable to deal with the mindfuck occuring in the frontal lobe of your brain.

May induce orgasms and mild strokes.
Human 1: "So anyway, I woke up this morning and realised my dad is actually a stripper.."

Human 2: "Fuck, what a Saw Twist"

Human 1: "I know, i thought he was a prostitute.."

Human 2: "Get help man, you're fucked."
by EyeHeartToast July 20, 2010