Top Definition
The effects of staying in Canada's most boring province for too long. Symptoms may include: Nausea, Boredom, Obesity, Severe headaches,Excessive fido fornication, and in severe cases losing your mind completley. Can be cured by moving somewhere populated, more exciting or beautiful
Doctor: Hmm, you say that he has been living in Regina for two months now? That explains it...I'm sorry M'am, your son has Saskatchewan Syndrome. I think if you want to cure him...move him somewhere very populated.
by Justine_Hawley March 02, 2009
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