(v) - to dominate a situation; to have control on something or someone
(syn): run this town
Lacreesha: Would you like to take this outside?
Kate: STEP THE FUCK BACK. I RUN THIS BITCH, HOE.
by zzil October 27, 2010
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One of the most basic terms in ebonics, this is essential to know. The word bitch is not necessarily derogatory in this case. Usually used to coax a laugh out of one's homies.
See Jane run. Run, bitch, run (for your life)!
~Sinfest
by Matthias Drake May 22, 2006
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To remove yourself from a bad situation in as quick a way as possible,mowing down anyone or anything in your way.
1.Oh shit it's the cops dude,run like a bitch!!!!

2.Guy 1:Is that a fucking zombie?
Guy 2:Run like a bitch!!!
by KillerKoolAid February 24, 2008
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either to run like hell to avoid a dangerous situation or from the cops... or to escape getting your ass kicked instead of fighting
1. I had to run like a bitch and jump the fence to avoid the cops!

2. Dude, instead of standing up for yourself, you ran like a bitch, now that fucker "owns" you!
by KingMidas July 11, 2008
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Originates from the interview scene with fictional character Shorty Meeks in Scary Movie.

In the era of internet memes, this is sometimes used in:

1. Video game footages, where you have no chance versus the approaching opponent or vice versa.

2. Any movie or video game scene, where a character attempts to bail (run for his life).
Shorty: I'm on T.V. Oh shit, first "Cops" now this. I'm gonna be a star, son!

Gail Hailstorm (Reporter): So how close were you to the victim?

Shorty: Oh real close. Right 'til the roofies wore and she woke up. Then she was all talkin' 'bout pressing charges so I just pulled my tongue outta her ass and left.

Gail Hailstorm (Reporter): If you could have spoken to her before she died, what would your last words to her have been?

Shorty: Run bitch run!
by BlazinItSince420AD November 24, 2015
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When you have to run as fast as you can from someone who is going to kick your ass
1. "Hey I fucked your girlfriend yesterday." "Brb!" "What?" " Better Run Bitch!!!"
by Sorry mate July 26, 2015
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When you run up to your bitch, smack her on the head real damn hard and/or fuck her real quick, and dip
Lamar’s ho was being disrespectful so I went to home run that bitch
by RulerOfThots September 18, 2018
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