Top Definition
A response or exclamation for when something bad happens or when an unpleasant event occurs.

It can be used as a personal exclamation or a response to someone else's misfortune.
Guy 1: Damn, I just broke my glasses.

Guy 2: Rough nuts, dude.
by dannyarcher March 21, 2011
1 more definition
Usualy a male who has not shaven or washed their face and hair for several days.
Hey Julian why don't you have a shave you rough nut !
by Goober II March 02, 2008

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