A disease typically caused by dew rags that leave indentations in the head and can possibly lead to death
Dew rags can cause rag rot
by Brain surgeon doctor smith November 6, 2018
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The premature thumbilation of your partners anus.

Dryrotting occurs when a foreign object enters the balloon knot wet but becomes dry while inside.
Dry-rot causes pain and discomfort when reattempting and ultimately ruines the off-road journey down that dirt road.
Y: babe stop. It hurts
M: I might have dry-rotted your asshole, my bad.
by Ass Mechanic April 5, 2021
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When a man has gangrene of the testicles, and they start to turn black and rot.

In which they begin to look like strawberries that are rotting.
I got a horrible case of rotting strawberries fresh from the vine.

My rotting strawberries smell really bad, and they are attracting fruit flies.
by CumCorpse October 6, 2023
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They are derived from staying in self-isolation in your room for too long. Common among gamers, who remain in their rooms for long periods of time without leaving to experience human contact. Therefore, they suffer from brain rot by being with themselves for so long.
"Have you seen Bill today?"

"Of course, not he's got room rot, haven't seen him for weeks."
by taylorswiftssidechick October 6, 2023
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When someone has delved into the recesses of twitter and start becoming infected with the obligatory "Twitter brain" where they make hypocritical or geopolitical statements with little to no grounding.
Woman: You can't say retard or the F slur! That's only for austists and/or gay men and the like to use because its been used against them!

Man: But I am autistic and gay, I just don't care to show it.

Woman: YOU SHOULD OWN BEING GAY AND HAVING AUTISM HOW ELSE WILL PEOPLE KNOW YOU CAN USE WORDS???

Man: I should want people to know what I have so they can know whether or not to police me? Twitter rot moment.
by Shwubblz, the Dictionary man November 12, 2021
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