Top Definition
The sensation that becomes travelers after 5+ hours in the car, particularly when driving at night. Road trip Insanity includes saying things that don't make sense, laughing hysterically at things that are not funny, and a general sense of "loopey-ness"
Once travelers have reached the point of Road Trip Insanity, there is not turning back.
Bob- I'm validated!
Tom- I'm inebriated!

Sally- Looks like you guys have a bad case of Road Trip Insanity.
by roadmaster1217 October 11, 2010
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