Top Definition
Also known as camarón de río. A highly contagious, quickly spreading disease originating in Harpers Ferry, WV. Although first reports in 2009 were contained within Harpers Ferry, numerous cases have since been discovered in outer states.

River Shrimp can not only be classified as an STD originating from shrimp (from the river) but as a threat to the human race as a whole.
Susan gave me river shrimp at the party last night, I don't know what to do!
by JamesthMD February 03, 2010

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