Top Definition
Rhode Island Syndrome: the act of meeting someone in a random place and knowing them from some other point in your life; this act must be repeated at leat twice a day to be considered RIS
Human: Dr. Thomas sent me over here to pick up my perscription.

Pharmiscist: Oh Joe? Yeah he just called. We were golfing earlier today.

Human: Really? How ironic.

Pharmiscist: Hey, did you go to URI?

Human: Yeah, I was a Ramett in class 1988, you look familliar...

Pharmiscist: I was class 1989! We must have Rhode Island syndrome.
by Star Gazer 13 April 07, 2011

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