A colloquial term for crack cocaine.Maybe.
Brass Eye TM - "have you got any quack handle?"
by John-O July 11, 2003
1 more definition
To be in a quackhandle is to be in the state of having too many mind altering substances taken at any given time.
phil got himself in to a serious quackhandle last night
by Jeimear November 10, 2010