Top Definition
A disease that causes the host to become a pansy and wear clothes from Aeropostale and Hollister.

Symptoms can range from: hanging around with lots of other Prepititis sufferers, being a cheerleader/football player, making fun of the more geeky types, and spreading stupid rumors about stupid people.
oh my gosh, those cheerleaders and their boyfriends have a severe case of Prepititis B.
by kisukeriley94 July 28, 2011

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