Top Definition
Slang term for the handgun cartridge .50 AE (50 caliber Action Express)
Mostly associated with the Desert Eagle Handgun.
From the movie "Snatch"

Bullet Tooth Tony: "And the fact that I've got Desert Eagle point five o."
*Withdraws his gun and puts it on the table*

Bullet Tooth Tony: "Written down the side of mine..."

*They look, zoom in on the side of his gun, which indeed has "DESERT EAGLE .50" etched on the side*
by Kintoshi2 September 28, 2009
5 Words related to Point Five O

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