Top Definition
A hooker that has almost every STD there is.Also she is morbidly anorexic and just sickening to lookat.Also they are addicted to to cocaine, herion and just about every other drug out there. And because of this she gets barely any business because noone wants to go near her out of fear.
Dude I say this guy pick up a Plague Whore yesterday it was fucking nasty.
by Dansquatch February 11, 2011

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