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a dog who has died from an std such as herpes, hepatitis c, gonorrhea , and/or tuberculosis
Tim: " I had a pikus may he RIP "
Abby: "Oh, how'd he die? "
Tim: " He got the clap..."
Abby: "o"
by shiloh willis December 26, 2009
A dude who sounds and acts like a chick; a pussy; a wuss. See Piko (Indian)
Piku: Hey I am Piku and I am such a woman, I whine like a little bitch.
by TenciaBeast October 25, 2006