1. When someone or something pisses you off. Like a pain in the ass but worse.

2. When something may cause your dick much pain.
1. "Cheryl, stop being such a pain in the dick."

2. Duffman- "Ya'll hear about suzie?"
Burnsy- "No what?"
Duffman- "I've heard she has vaginal teeth."
Burnsy- "What a pain in the dick."
by Young Burnsy January 27, 2010
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A female that continues to nag and complain even after all avenues and attempts at resolution are reached.

An attempt to end an argument by associating yourself with the problem and by not call a woman a derogatory name or phrase.
Woman: nag, nag nag nag, nag, nag nag nag.

Man: Yes, maybe, ok, no, sorry, right.

Woman: nag, nag, nag, nag nag nag, nag nag, nag.

Man: You are a pain in my dick.

or

Man: I have a pain in my dick
by mufalleto March 3, 2011
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