An acronym for "Piss on the fuckin' Hoosiers." It is commonly used in God's country: West Lafayette, Indiana.
"When I went to this shitty party in Bloomington, I took a POTFH."
Piss On The Fucking Hoosiers. Commonly used on the Purdue University, West Lafayette Campus, in reference to the Indiana University Hoosier athletic teams.
Joe: "Dude, IU is kind of good this year, if they get 1 more win, they could go to a bowl game."
Dave: "I don't care. POTFH. The Boilers are gunna murder them."