RPG refers to Role Playing Game; See RPG.

Open PvP is a term used in RPGs to describe the freedom of a RPGs world. PvP refers to Play vers Player. Open refers to any play can compete with another player in any given way.

In the context of a RPG, they would be competing with another player for a reason that fits their characters role. If they attack everyone, they could be considered a murderer. In that role they could expect the game to hunt them and a life of hiding with other outlaws.
"The game was an Open PvP RPG. I was Role Playing a Murderer and would try to kill other players. The games NPC Police were out to get me so I had to hide often."
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