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a commonly used nickname for the town of Olney, MD. it is used by teenagers more frequently than any other age group.

it is occasionally mistaken for Orlando, FL. Orlando is not a definition of O-town. This is also true for other cities and towns beginning with an "O" other than Olney.
A: Yo man, you in the 301?
B: yea son. I'm in O-Town.
by o-town resident January 08, 2011
3 19
The city of Orlando. Orlando, FL
"Where's o-town? In central Florida"
by alex August 03, 2004
250 98
Shortened term for Orlando, Florida.
We be too crunk down in O-Town.
by Sessa October 18, 2005
136 81
O Town Is Oakland, CA
Where's Tupac From?
O Town Bitch
208 155
Regardless of what all these other bullshit entries say, otown is most widely known as the nickname of Orlando, Florida. Not fucking ottowa or ohio or whatever.
Homie:Yo dawg lets go to orlando, also known as O-town.
by Dick F. April 08, 2009
95 52
The central city of Florida:Orlando.
We have groovy times in the theme parks at Otown.
by Maries April 22, 2006
72 42
a name for Orlando Florida
Going to o town for the weekend
by moester December 12, 2007
79 64
Nickname for many cities beginning with the letter 'O'. Anyone living near such a city believes their city is the only true O-Town.
Ottawa, Canada is known as O-Town.
by Mister Marbles September 24, 2010
30 28