1. In response to someone who has said/pointed out that you did something wrong
2. In response to someone has confronted you about how you insulted them or aggressively disagreed with them
3. In response to a boring, nerdy comment you don't understand or care about (i.e. a peice of trivia)
4. In response to a comment that seems like overwhelming evidence proves that you are dead wrong
Occasionally some will respond to an "O sry?" comment with "ya sry" or "sry", but this is lame and not recommended.
B: O sry? I didn't see it
2. A: You're a fucking loser, A Cinderella Story was a shitty movie.
B: O sry. I shouldn't have forced you to watch it with me.
3. A: Yes, but did you all know that the word "catapult" is of Hungarian and French origin and roughly translates to blah blah blah......
B: O sry? I never learned anything as useless as that.
4. A: My aunt is friends with Lindsay Lohan's agent's sister, and she's said that Lindz is totally not a cokehead, so stfu.
B: O SRY?