Top Definition
When a person takes a massive dump in another persons microwave and cooks it on the highest setting until it explodes into a shitty mess or catches on fire. The Nuke Duker normally flees the scene so that when the owner of the microwave finds the evidence, they are none the wiser.
I was at my best friends house and he drank all my beer, so while he was at work, I ate everything in his fridge and then left him a Nuke Dukem.
by Steven Langston April 09, 2007

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