The feeling one gets after racking up your first 24 killstreak in Call of Duty Modern Warfare 2 and having some douchebag runner knife you in the back preventing you from getting your nuke on. Much like the feeling of having your girlfriend lovingly suck on your penis and wait till you are about to cum but instead, headbutts your balls.
Gamer: DUUUDE I almost got a Nuke on wasteland!!!!!

Roomate: Fuckin tits dude

Gamer: Right? Ive been trying all week!! Wait, why do my balls hurt so bad all the sudden?

Roomate: Dude, youve got Nuke Balls .....
by gman527 August 31, 2010
Get the Nuke Balls mug.