The large vein running down the side of your leg, along side the calf. Most commonly seen in runners, the Nate Vein can be seen and interpreted as sexy or manly by females, especially other female runners. Usually meaning the person is of great importance or speed to a cross country/distance running team. Named after high school state silver medalist in the mile run, Nate Mclafferty.
Do you see how well defined that kids Nate Vein is? He must be fast!
by XCprince323243 June 19, 2011