Drugs or anything that has to do with drugs of any kind.
"Dude I smoked so much Mr. Mo last night I was high as a kite."

Dude #1: "Hey man, how's the Mr. Mo going?"
Dude #2: "Shitty. I still got three twennys to get rid of before I re-up."
by Daily Compulsion August 26, 2009
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