Top Definition
A play on the coined saying, "Freshman 15" where college students are known to gain at least 15 pounds as a result of being off a strict diet, and having access to a variety of dining halls that are provided by their schools.

The "Mizzou 22" is where students (of the University of Missouri) shed 22 pounds as a result of the amazing rec. center that the school has to offer, as well as the utmost dedication that Mizzou students have to stay fit & healthy. GO TIGERS!
Everyone is dreading gaining the "Freshman 15" next year, but I am really looking forward to losing the "Mizzou 22" at the gym!
by MizzouTiger July 14, 2014

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