Top Definition
Named for Mikes Hard Lemonade, which everyone knows is a drink for women, but is probably really good, and if you drink it once you will like it and order it out with the guys and they will ridicule you forever.

Can be applied to addictive things (drinking, smoking, certain foods) or just things you don't want to like (appletinis, teen dramas on tv, crocs)
Michael is watching One Tree Hill again. He watched that crap once and now he is suffering from the Mikes Hard Effect.
by UNCFrady September 08, 2008

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