Top Definition
A semi-uncommon disorder among Mexican immigrants, MDS consists of a total lack of knowledge of American culture and language. Phrases such as "Come over, i'll cook you", "I love the smell of burn", "Can I use powerful words?", and "Smelt" are used frequently. Patients diagnosed normally don't have many friends, and are give shit by nearly everyone.
Jay: Did Rosa just say,"Shit my hole"?

Matt: Give her a break, her doctor says she has a case of chronic Mexican Down Syndrome.

by Richard Pancreas February 21, 2009
6 Words related to Mexican Down Syndrome

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