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A piercing located on the top lip, in the middle, just below your septum.

Generally worn with a labret post, Medusa piercings are incredibly painful.
"See that piercing on her top lip?"
"Yea?"
"It's a medusa."
medusa by nekr0phel3ah September 17, 2006
A woman with a severe case of resting bitch face that it turns you to stone.
Vic: Don't look at that girl.
Paul: Why?
Vic: She is a Medusa. You will turn into a statue. That's how strong her resting bitch face is.
Medusa by ao218 February 1, 2015
The girl at the party who always has weed to share. She'll get everyone stoned.
Glad we ran into a Medusa last night, everybody was lit by the time she left
medusa by medusalover September 2, 2010
A woman that's so unbelievable hot one look at her and you instantly get wood (or turn to stone)
One look at that blonde Medusa and I was ready to put in some work!
Medusa by Da Count October 8, 2005
It is another word for a blunt, which is a cigar that is hollowed out and filled with cannabis. It is in reference to the myth of Medusa, where anyone that saw Medusa's face would be turned to stone. The blunt itself will get the person smoking it high, or "stoned".
Jeff was cold rolling a Medusa on his kitchen counter.

Austin asks his friend to pass the Medusa.
Medusa by kuppalli October 27, 2014
And how do you defeat a Medusa?
Hym “And how do you defeat a Medusa? You hold up mirror.”
Medusa by Hym Iam October 20, 2022