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A person under the influence of prescription pain medication whose personality and emotions completely disappear. This person will act like a shell of a human being that is being controlled from a remote location (i.e. a drone).
Mike: What was wrong with Brian last night? He didn't seem like his normal self.

John: It must be because he's taking some really strong pain medication for his back.

Mike: Well that explains why he was acting like a medicated drone.
by Sparkles1974 March 20, 2012
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