1. referring to a general state of machismo affecting persons over a vast geographical area.

2. a highly contagious state of brodaciousness, or brovado, raising levels of brogesterone to dangerous levels.
What began as a modest brodown soon escalated into a full-fledged mandemic as hordes of the broletariat, as well as the brogeousie, converged on the streets, almost as if the brozone layer itself were replete with brogesterone and raining it down upon bros en masse.
by Alpha Cat November 1, 2010
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your crew/gang that you go around with and get in trouble with, usually 4-6 people.
teacher 1: Best get in isolation right now.
girl 1: No chance,not without my mandem.
girl 2,girl 3,girl 4: Get iso on friday mandem cause fishy's on duty first break,it'll be a laugh
by greenblazer April 4, 2019
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Referring to a place or situation dominated by men or males
I went to the club on ladies night to hook up and it was a mandemic inside. Three females 59 dudes
by Breaking dancing on cardboard October 11, 2020
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An expression of mild to medium annoyance or aggravation, usually directed at an animal or inanimate object, often confused with 'mandem'.
"Joe your pizza is burnt"

"Aw MANDEMS!"
by future_cat_2 October 24, 2009
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just basically meaning a group of friends
Person 1: "I'm sorry I won't do it again
Person 2: "Ye fam, don't mess wit me and my mandem
by chrisnator101 April 2, 2017
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