Top Definition
Pain and/or weakness in the hands and wrists caused by prolonged playing of Pokémon.
Gary: "Dude, is that an old-school Game Boy? What are you playing?"
Ash: "Pokémon Red."
Gary: "Awesome!"
Ash: "Yeah, except Magikarpal tunnel set in an hour ago, and my hands are killing me."
by Salmoon and Clownboat November 28, 2010
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