Top Definition
1) The occurrence of having one remaining piece of any given food substance at a table of multiple people. This "Last Piece" will be stared at and ogled, but never eaten until cold, as nobody wants to appear a pig.
Marsha: We have one piece of oreo pizza left.
Brendan: Yes, I can see that, you dumb ho.
Marsha: You can have it.
Brendan: No, I'm full, you go ahead and eat it.
Marsha: I'm full as well.
Brendan: How about we split it?
Steve: Actually, since you two are busy with Last Piece Syndrome, I'll go ahead and eat it myself.
by Pandaster September 10, 2009
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