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Jesus, Mary, and Joseph 

The pinnacle of Catholic blasphemous interjections. Often shouted, and done so only when the situation calls for it.
*A giant brown bear runs into the middle of the road, as you are driving down it*

You: JESUS, MARY, AND JOSEPH! *Swerve*

Jesus, Mary, and Joseph 

Nikocado Blablablado's catchphrase.
Nikocado: *does something* Jesus, Mary, and Joseph!
Jesus, Mary, and Joseph by rl90599 September 5, 2020

Jesus, Mary and Joseph on a pogo stick!

The irreverent, blasphemous, Catholic-blasting exclamatory phrase used when a stupid and funny event occurs.
Lars was so drunk that he left his house in his tidy-whiteys without his pants, went to the corner store, and brought back a six-pack.

You: What an idiot! Jesus, Mary and Joseph on a pogo stick!

Jesus, Mary and Joseph 

A extremely Christian phrase, usually practised by white 23 year old virgins trying to become more christian after their uncle Dave criticised them for that car they bored... stole.
White christian: (spills coffee) Oh Jesus, Mary and Joseph!
anybody else accept from very white Christians: Whaaaattttt!

Dear jesus mary and joseph edward i’m arriving 

Becky:Dear jesus mary and joseph edward i’m arriving‼️‼️

Jesus Mary and Josephed 

To get sooooo drunk you don't remember anything the next day.
Oh man, i was so Jesus Mary and Josephed last night, my head is banging.