Top Definition
Blue balls make you angry, upset, agitated and irritable.

After getting aroused for a while and then not getting off is irritating.

If a girl is known for giving guys blue balls she can be labelled IBS.
Mitch "Yo, why are you sitting with your legs so wide apart and your belt undone?"

Corey "That tease Brandi gave me Irritable Ball Syndrome again."

Mitch "IBS, sucks to be you."
by Lawrencetown April 11, 2013

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