Top Definition
When, after an epic night of drinking where your problems don't matter, you wake up in the morning and all of your life's problems come rushing at you at once. This usually leads to you sitting on the edge of your bed with your head in your hands, just contemplating all the ways you can attempt to fix your life.
Last night was such an epic night! I woke up with the worst case of Infinite Sadness this morning though.
by AlphaCaveman August 19, 2010

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