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Being intelligent, drug-using, sarcastic, talented, insensitive, narcissistic, misanthropic, a jerkass, or in any other way greatly resembling Doctor Gregory House. Can be an expression of admiration as well as derogation.
- Wow, you're so Houseish!

- Imma go take some vicodin.
- Dude, don't be so Houseish!
by lerandomshizz. June 18, 2010