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Refers to traveling out of your way to intentionally come into contact with gorgeous members of the opposite sex.

Can be done by foot, but is preferably done in an expensive and flashy vehicle. The path traveled usually takes one by a certain locale where said hotties are known to congregate. Can also refer to following a particularly sexy person for a short time, or dawdling near them.
Guy 1: "Hey man, sorry I'm late. I ran a hot route in my bother's new car on the way over here."

Guy 2: "No problem dude. See any fine looking women?"

Guy 1: "Hell yeah! Got some numbers too."
by don't be that guy September 28, 2009
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The act of dipping your dick in hot sauce for lubrication while fucking.
"She said she liked it spicy, so I gave her a hot-route"

"bitch made me buy her 11 drinks, so I hot-routed her"

"That exam just hot-routed me!"
by lulibrary December 26, 2012
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