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1.
Phrase one says when:

One is having a very bad time in life.
When one has had too much drink or food or medication.
When one is out of control.

Taken from the 60's Cartoon "Tooter Turtle" Tooter would call on Mr Wizard for help.
Help Me Mr Wizard! I'm too drunk to get up"
Help Me Mr Wizard! I'm having PMS"
Help Me Mr Wizard! I'm spazzing out"
by Cheryl_SF November 05, 2006

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