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When all hope is lost.
When you run out of gas in the desert, with no water or cell phone, you might say that you are: "Gun Fucked."

"Gun fuck me with the blunt edge of a knife, I spilled all my fucking booze and the stores and bars are closed."
by LATTIN July 19, 2009
The act of using a weapon(usually an unloaded pistol or shotgun) in an act of sexual penetration.
...so I shoved the shotgun as far up her pussy as possible and proceeded to gunfuck her.
by M.R. May 29, 2004