The pain that gets shot into your wrist or hand after playing any of the three guitar hero games for too long.
"Dude, why is your wrist in a cast?"
"I played Guitar Hero 3 for 5 hours non-stop and got Guitar hero-itis"
"I played Guitar Hero 3 for 5 hours non-stop and got Guitar hero-itis"
by Wally Furrer October 29, 2007