Top Definition
gug-e-o-knee.
This is two horrible describing words mixed together to form a ultimate put down. Gug meaning a person who resembles a gay insect and Regione, a name you call some one who is just bad at sports, smelling, good being a friend. Just life in general. In fact the oly good trait of a Gugione is able to wank more than the average man.
Man your just shit at life, your such a Gugione.
by Jakey Dildo June 22, 2012

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