Top Definition
A disease which is the result of a large build up of gas, passed on to nearest person, other person starts farting frequently - and whiffing.
Cor Emma.. you've given me your guffitus i can't stop farting, and i whiff!

Oooop, Emma has guffitus again

Oh hell no i've caught Guffitus from you, my word i stink!
by Stacey and emma October 15, 2007
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