Top Definition
This word originated in southern California in the early 2000's. A Gueeze is A close companion with whom a majority of your time is spent, the relationship could be completely platonic or romantic. one cannot simply refer to a new friend as gueeze, it its a title earned by loyalty and trust and it takes time. A gueeze is another word for road-dog.
"I love chilling with my gueeze" or "Hey gueeze pass me the ketchup"
by bfrizzy March 17, 2013

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