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3.
bat-shit crazy
Neil Halelamien is guano loco, man!
by tagonist July 15, 2009
 
1.
Batshit Insane.

Crazy, in fact probably totally insane.

Acting in the manner of Tom Cruise jumping on Oprah's sofa or Joaquin Phoenix on the Letterman show.

Hearing voices and imagining things that haven't happened or people saying things that they haven't.

Possibly caused by some recent trauma, however more than likely always present just brought to the surface in times of high emotion.
Person 1: "What's up with that girl talking to herself?"
Person 2: "She's been totally Guano Loco since her boyfriend moved to Greece and dumped her ass"
by Bush Girl September 04, 2009
 
2.
someone who is bat shit crazy
almost all politicians are guano loco
by J.Richard December 18, 2007