Top Definition
The phenomena that occurs in infomercials where the video becomes black and white and the simplest tasks are impossible without the product being sold in said infomercial
Vince from Shamwow: Its not possible to wipe up a spill you just spread it around and everything goes black and white thats why you need shamwow.
Me: Thanks to grayscale syndrome they'll sell a million sham wows
by Homgen4 January 28, 2009
5 Words related to Grayscale syndrome

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