To literally or metaphorically kill, destroy, or defeat someone/something.

*Better understood if you're from Long Island, NY or are at least familiar with the Gilgo Beach murders*
Also- it always sounds better if you add the word "though" at the end.
That test was so hard...
Na, I Gilgo'd that hoe tho!

or...

I can't believe all this food, it looks so delicious...
We gon Gilgo that hoe tho!
by SamanthaPatricia December 04, 2011

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