Top Definition
To make a bad judgement call and sleep with a person who is particularly ugly and kinda crazy, rather like Gary Busey. Extra points if they resemble Gary Busey perfectly, especially if they have freaky teeth.
Friends are henceforth required to sing "Getting Busey With It" to the tune of Will Smith's "Getting Jiggy With It" and never let them live it down.
Girl: Dude, check out that gross toothy girl he's with.
Boy: I know, he's totally getting Busey with it.
Both: Na-na-na, na-na, na-na!
by Squisha February 03, 2010
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