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1.
It means "Google Is Not My Friend."
Its what you say when you ask a stupid question, and before you can recant, someone tells you "GIYF." The other usage is when you ask a question that others presume are stupid, and so they tell you "GIYF," but even though you used Google, you can't find the answer.
A:
You: What's the worst band ever?
Other Guy: GIYF
You: Bah, GINMF

B:
You: How do I turn off quaternion interpolation in Poser 7?
Other Guy: GIYF
You: GINMF
by Robert Storm August 27, 2007