Acronym for god-damn mother fuckin' son of a bitch.
Joe called Sally a G.D.M.F.S.O.B. after she tried a dirty-sanchez Hitler combo on him.
by Russian Love April 30, 2005
God Damn Motherfucking Son Of a Bitch
DJ Shadow feat. Roots Manuva - GDMFSOB (U.N.K.L.E. Uncensored Mix)
by Krusher November 20, 2006
God damn mother fuckin son of a bitch!
"God damn mother fuckin son of a bitch! I can't move, I can't twitch!"
by Mike Pissoff November 14, 2003
god damn mother f***ing son of a bitch
she called me a gdmfsob!
by lerryn August 01, 2005